What Is CBN? (Cannabinol)

Two of the 100 natural chemical compounds called cannabinoids, cannabidiol and cannabinol, are found in cannabis plants.

Tetrahydrocannabinol, the psychoactive compound in marijuana that gives you a high, is something you may have heard. CBN and CBD are milder than THC. They aren’t psychoactive and won’t affect your mind. They are instead praised for their medical benefits.

They are not the same. Although CBD and CBN interact with similar receptors in the body, they produce distinct effects.

CBD is more well-known than CBN. CBD is mainly derived from hemp plants and is legal for consumption. But state laws vary. CBD-infused products can be found in everything from grocery stores to gas stations. You can find it in many beauty and food products, including oils, creams and pills, as well as chocolates and shampoos. It is often used to manage anxiety, insomnia, and other chronic pain conditions.

CBN is, however, not as well-known or easily available. Because there isn’t much research on CBN’s benefits, uses, or side effects, neither have animal studies. CBN is slowly becoming more popular for its potential benefits in pain management and sleep.

CBN is less well-known and used than CBD and THC. However, it has shown promise in treating certain conditions. Find out more about this lesser-known cannabinoid, including its potential side effects and benefits.

What is CBN?

Cannabinol (CBN), a cannabinoid, is found in cannabis sativa plants. It can also be synthesized.

CBN is formed when THC undergoes degradation due to exposure to heat and/or light. Eric Adams, CEO and president of InMed Pharmaceuticals (a developer and manufacturer of rare cannabinoids), says that higher levels of CBN are possible in older, dry cannabis. CBN doesn’t have the psychoactive intoxicating effects of THC.

CBD vs. CBN – What’s the Difference?

Cannabidiol, or CBD (Cannabidiol), is one of the most well-known cannabinoids in cannabis sativa plants. CBD, although it is similar to CBN in that it doesn’t come directly from THC but exists within the plants.

CBD has been extensively studied in clinical settings more than CBN. It’s also more common in mainstream retail products. While CBD has many therapeutic benefits, CBN is not yet able to match that list.

The benefits of CBD include, but are not limited to:

  • Anxiety and depression symptoms can be relieved
  • Pain relief for multiple sclerosis, nerve damage and cancer patients
  • Reduce arthritis symptoms
  • Two rare forms of epilepsy, Dravet syndrome and Lennox-Gastaut Syndrome, are addressed
  • Other interventions may also be used to treat opioid addiction

CBN and CBD both bind to CB2 receptors within the body’s Endocannabinoid System. This system plays a key role in central nervous system function. It also helps the body respond to external stimuli. The immune system regulates CB2 receptors.

Pure, premium, and powerful CBD

FAB CBD products are made with organically grown and lab-tested Colorado hemp. There are many products available, including CBD oils, CBD gummies, topical CBD creams, dog treats, and CBD oil.

CBN has potential benefits

Although research on CBN is limited, particularly in human clinical trials, some preclinical studies have suggested that it could be used as a therapeutic agent.

Treatment of Epidermolysis Bullosa

CBN cream is being tested by researchers as a treatment to epidermolysis bullosa. This rare condition causes the skin to blister quickly. InMed Pharmaceuticals is currently in the second phase. They found that CBN cream was well-tolerated by normal skin and open wounds. There was no delay in wound healing .

Eric Hsu is senior vice president of preclinical research at InMed Pharmaceuticals. He believes that CBN could have an anti-inflammatory effect that could help heal chronic wounds.

Glaucoma: How to Reduce the Symptoms and Effects

InMed Pharmaceuticals’ research suggests that CBN could be helpful in treating eye conditions such as glaucoma. This condition causes vision loss and blindness, and damages the optic nerve at the back of your eye. Glaucoma is often associated with high eye pressure. It is possible to lower that pressure and slow down the condition.

InMed Pharmaceuticals’ vitro Study found that treating certain retinal cell types with a topical CBN formulation resulted in high levels of cell survival under elevated pressure. These tests showed that CBN was more effective than CBD and THC. CBN may also have neuroprotective properties, which means it can protect nervous system structures and cells by significantly reducing or even preventing natural cell deaths.

How to relieve chronic muscle pain

A 2019 study on rats found CBN–as well as CBD and a mix of the two cannabinoids–decreased muscle sensitization. Researchers believe CBN may provide pain relief for chronic pain conditions such as temporomandibular disorder (pain in the jaw muscles and joints) and fibromyalgia, but clinical trials have not yet been conducted.

CBN: Side Effects and Potential Risks

It’s not possible to determine how CBN affects the human body without conducting clinical studies. CBN can cause drowsiness, sedation, and positive drug tests.

Drowsiness or Sedation

Drozziness can be a side effect of CBN, particularly when it is combined with CBD. Laura Fuentes is a licensed compounding pharmacist who is also the chief scientist and innovator for Green Roads CBD products company.

She says that CBN products should not be taken during the day because of this. “We will continue to learn more about drug interactions and side effects as more research is done.”

CBN products are often used by consumers to aid in relaxation and sleep. In these cases, the benefits might be considered as potential benefits.

Positive Drug Test Results

“There are evidence that CBN could inadvertently cause failed drug tests,” states Mark Ratner M.D. Chief science officer at Theralogix a nutritional supplement company.

CBN was found to have a positive effect in at least two drug tests. In one test, CBN also showed an “additive affect” with THC. This essentially increased the appearance of THC . Even if your THC levels were low, CBN can cause your levels to rise, which could lead to a positive drug test.

CBN Products – Where to Buy

You can find many options among the top CBD brands if you decide to try CBN products. When sourcing cannabis products make sure that the company is:

  • All its products have a certificate of analysis. This document should detail the exact levels of cannabinoids and the presence of heavy metals or pesticides.
  • Third-party testing. To avoid conflicts of interest, biases, and inaccuracies on labels, a company should send its products for independent testing to a third party laboratory. For more information, you can look into third party labs.

How to Use the CBN

Before you consume CBN, consult a doctor.

CBN, like CBD, can be found in many forms. The most common are oils, tinctures, gummies, or capsules. It is more common to find CBD products containing CBN than CBD products only.