What Is CBC? (Cannabichromene)

Cannabichromene is a non-psychoactive cannabis cannabinoid. It is usually found in the tropical strains of cannabis and has strong anti-inflammatory, anti-bacterial properties. Recent research has shown that cannabichromene may inhibit the growth of cancerous tumours. CBC also binds to the body’s molecular systems responsible for regulating and balancing different processes.

Its potential use in the fight against cancer is further encouraged by this. CBC offers many benefits, including the ability to fight bacteria or fungus and reduce swelling. It can also elevate your mood. There are three types of CBC cream: oil, extract, and cream. CBC cream can be used to treat acne. It soothes the skin’s sebaceous glands, which may produce excessive oil.

CBD is the focus of much more research. Recent discoveries point to the additional benefits of CBC.

You are probably already familiar with cannabinoids, particularly the most popular ones, THC or CBD. You may not have heard of cannabichromene (also known as CBC). CBC was discovered over 50 years ago and is one of the most prominent cannabinoids in medical research. Although it doesn’t receive as much attention, CBC’s potential benefits are very promising.

CBC is the same as CBD and THC in that it comes from cannabigerolic (CBGA) acid. Cannabis plants produce CBGA, the precursor to three major cannabinoids: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).Related: A list of the major cannabinoids found in cannabis and their effects

Specific plant enzymes “direct” the breakdown product to one of these lines by cascading. For CBC, it transforms CBGA into cannabichrome carbonoxylic acid (CBCA) and finally to CBC when exposed to heat or UV light.

CBC Works with Other Cannabinoids

CBC is not intoxicating and doesn’t give off a high like THC. It is not intoxicating because it does not bind well to CB1 cannabinoid cells in the brain. CBC can bind to other receptors within the body, including the vanilloid receptor 1 and transient receptor pot ankyrin 1. Both of these receptors are related to pain perception. These receptors are activated by CBC, which results in increased levels of natural endocannabinoids such as anandamide.

Although CBC has its own benefits, researchers believe it may also work in conjunction with other cannabinoids. This is called the entourage effects. Although this effect of CBD and THC working together is well-known it isn’t clear if other cannabinoids may have entourage effects.

CBC’s Medicinal Potential

The purported benefits of CBC can have wide-ranging implications. Here are some medical conditions that can be helped by cannabichromene.


Cannabichromene could be an effective cancer fighter. This may be due to its interaction with the body’s natural endocannabinoid. CBC appears to block the uptake of anandamide and allow it to stay longer in the bloodstream.

Recent studies in mice that showed tumor growth (two-stage mouse skin cancergenesis model) suggested that cannabinoids may be effective in inhibiting inflammation and tumor growth. Anandamide has been proven to combat breast cancer both in vitro as well as in vivo. This suggests that CBC and other cannabisoids may one day be a chemopreventive drug.

CBC was first identified as a possible cancer fighter in a 2006 study. This study examined cannabinoids other that THC and how they might affect cancer. Despite being known for its anti-tumor effects on many types of cancer, THC’s powerful psychotropic properties can make it difficult to use for chemotherapy. Research has shown that CBC is the second most potent cannabinoid in inhibiting growth of new cancer cells ( CBG was by far the strongest).

Inflammation and Pain

Cannabichromene has been proven to reduce pain and inflammation related to collagen-induced osteoarthritis. CBC and other cannabinoids act differently on inflammation than non-steroidal antiinflammatory drugs (NSAIDs). They also don’t have side effects. Another example of the entourage effect is that CBC and THC produced a significantly greater anti-inflammatory response in a animal study.

Brain Cells

A 2013 mouse study showed that CBC had a positive impact on neural progenitor cell (NSPCs) which is an essential part of healthy brain function. CBC made NSPCs more viable. This is because NSPCs can differentiate into astroglial cell, which are the most critical cells in maintaining brain homeostasis. Astroglial cells perform many functions including neurotransmitter direction, and protecting against oxidative stresses. Astroglia combat many of the issues, including inflammation, toxicity, oxidative stress and toxicity, that can lead to neurological diseases, such as Alzheimer’s, and other brain pathologies, like Alzheimer’s.


The effects of CBD on acne were previously demonstrated by a research team. They also studied other cannabinoids and CBC for similar results. CBC has been shown to be a strong inhibitor of acne. Acne is characterized as excessive sebum production and inflammation of the sebaceous glands. CBC had powerful anti-inflammatory properties. It also reduced excessive lipid production in the skin glands. CBC also decreased levels of arachidonic acids (AA), which are necessary for lipogenesis. Although more research is required, CBC could one day be a powerful anti-acne treatment.


Another amazing example of the entourage effect is that CBC appears to work with THC and CBD to provide a triple combination of antidepressant properties.

It is important to understand the therapeutic potential of CBC. More research will be needed to establish its power as a single compound and with other cannabinoids that work together to create an entourage effect. Today, cannabis patients have limited options for products, but as more research is done and the laws are relaxed, new cannabinoids-based medicines will be available.